Trace mineral changes in response to organic and inorganic selenium supplementation

Document Type : Research Paper

Authors

1 Department of Clinical Sciences, School of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

2 School of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

3 Department of Basic Sciences, School of Veterinary Medicine, Shahrekord University, Shahrekord, Iran

4 Faculty of Medicine, International Campus of Shahid Sadoghi Medical University, Yazd, Iran

Abstract

Twenty-one Lori–Bakhtiary sheep were randomly allocated into 3 groups to compare the effects of oral selenium nano particles (Se NPs) and sodium selenite (Na-Se) supplementation on serum selenium, copper, zinc, molybdenum, manganese and cobalt concentration. Groups 1 and 2 orally received Se NPs and Na-Se (1 mg/kg) for 10 consecutive days, respectively and group 3 were considered as control group. Blood samples were taken on the days 0, 10, 20 and 30, and minerals were measured using atomic absorption spectrophotometery. The obtained results showed that selenium, copper and manganese concentration increased and zinc level decreased significantly in both treated groups (P<0.05). In addition, serum molybdenum concentration increased in response to oral Na-Se supplementation on the days 10 and 20 compared to the basal level and also the control group (P<0.05). Findings explain the interaction between selenium derivates and other elements in which the role of Se NPs was considerable in increasing Cu and Mn level and the role of Na-Se noticeable increasing serum molybdenum concentration.

Keywords

References

References
Albrecht, M.A., Evans, CW. & Raston, CL. (2006). Green chemistry and the health implications of nanoparticles. Green Chemistry 8, 417–432.
 
Anderson, D.E. & Rings, D.M. (2009). Current veterinary therapy, food animal practice, WB Saunders, St. Louis, Missouri. 5th Volume 
 
Constable, P.D., Hinchcliff, K.W., Done, S.H. & Grunberg, W. (2017). Veterinary Medicine, A text Book of the diseases of cattle, horses,sheep, pigs & goats,. Elsevier, St. Louis, Missouri. 11th  ed.
 
House, WA. & Welch, RM. (1989). Bioavailability of and interactions between zinc and selenium in rats wheat grain intrinsically labeled with 65ZN and 75Se. J. Nutr. 119, 916-921.
 
Hu, CH., Li, Y.L., Xiong, L., Zhang, H.M., Song, J., & Xia MS. (2012). Comparative effects of nano elemental selenium and sodium selenite on selenium retention in broiler chickens. Anim. Feed. Sci Tech, 177, 204-210. 
 
Jacob, C., Maret, W. & Vallee, BL. (1999). Selenium redox biochemistry of zinc–sulfur coordination sites in proteins and enzymes. Proc. Nat. Acad. Sci. 96, 1910–1914.
 
Kojouri, GA. (2006). The status of cobalt in soil, plants and animals in Shahrekord district, northwestern Iran. Iran. J. Vet. Res. 7, 66-69.
 
Kojouri, GA., Ebrahimi, A., & Zaheri, M. (2009a). Zinc and selenium status in cattle with dermatophytosis. Comp. Clin. Path. 18, 283-286.
 
Kojouri, GA., Jahanabadi, S., Shakibaie, M., Ahadi, AM. & Shahverdi, AR. (2012). Effect of selenium supplementation with sodium selenite and selenium nanoparticles on iron homeostasis and transferrin gene expression in sheep: A preliminary study. Res. Vet. Sci. 93, 275–278.
 
Kojouri, G.A., Rezakhani, A. & Ahmadi, H. (2009b). Arrythmias in advance stiff lamb disease. Small. Ruminant. Res. 84, 65-69.
Kojouri, GA. & Shirazi, A. (2007). Serum concentrations of Cu, Zn, Fe, Mo and Co in newborn lambs following systemic administration of vitamin E and selenium to the pregnant ewes. Small. Ruminant. Res. 70, 136-139.
 
Mehdi, Y., Hornick, JL., Istasse, L. & Dufranse, I. (2013). Selenium in the environment, metabolism and involvement in body functions. Molecules, 18, 3292-331.
 
NRC., (1982). United States-Canadian Tables of Feed Composition.. Washington, DC: National Academy of Sciences-National Research Council. 3rd ed
 
O'Dell, BL. (1989). Mineral interactions relevant to nutrient requirements. J. Nutr. 119, 1832-1538.
 
Pan, C., Huang, K. & Zhao, Y. (2007). Effect of selenium source and level in hen’s diet on tissue selenium deposition and egg selenium concentrations. J. Agric. Food. Chem. 55, 1027–1032.
 
Qin, S., Gao, J. & Huang K. (2007). Effects of different selenium sources on tissue selenium concentrations, blood GSH-Px activities and plasma interleukin levels in finishing lambs. Biol. Trace. Elem. Res. 116, 1, 91-102.
 
Sadeghian S., Kojouri GA.& Mohebbi A. (2012). Nanoparticles of selenium as species with stronger physiological effects in sheep in comparison with sodium selenite. Biol. Trace. Elem. Res. 146, 302–308.
 
Smith, B.P. (2015). Large animal internal medicine.., WB Saunders, St. Louis, Missouri. 5th ed
 
Surai, P.F. (2006). Selenium in nutrition and health. Nottingham University Press, Nottingham, pp. 363-588.
 
Underwood, E.J. & Suttle, N.F. (1999). The Mineral Nutrition of Livestock. CABI Publishing, Oxon, U.K. 3th   ed.
 
Waghorn, G.C., Shelton, ID. & Sinclair, BR. (1990) Distribution of elements between solid and supernatant fractions of digesta in sheep given six diets. New. Zeal. J. Agr. Res. 33, 259–269.
 
Wang, H.L., Zhang, JS. & Yu, HQ. (2007). Elemental selenium at nano size possesses lower toxicity without compromising the fundamental effect on selenoenzymes: comparison with selenomethionine in mice. Free Radical Biol. Med. 42, 1524-1533.
 
Zhang, JS., Gao, XY. & Zhang, LD. (2001). Biological effects of a nano red elemental selenium. Biofactors. 15, 27-38.
 
Zhang, J.S., Wang, XF. & Xu, T.W. (2007). Elemental selenium at nano size (Nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with Se-methylselenocysteine in mice. Toxicol. Sci. 101, 22-31.
 
Zhang, S.Y., Zhang, J., Wang, HY. & Chen, HY. (2004). Synthesis of selenium nanoparticles in the presence of polysaccharides. Mater. Lett. 58, 2590-2594.
 
Iranian Journal of Ruminants Health Research
Volume 2, Issue 1
April 2017
Pages 39-45

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